Naknek is home to the Bristol Bay Historical Museum, featuring archaeology, history and Native culture, and documents the town's history as one of the largest commercial salmon fishing and canning headquarters in the world. The museum building is the original Fisherman's Hall, an early meeting place for fishermen.
Charter boat operators based in Naknek offer salmon and halibut fishing in Bristol Bay as well as marine wildlife excursions from the village.
The Russian Orthodox St. John the Baptist Chapel in Naknek, reportedly constructed in 1886, is on the National Register of Historic Places.
Alaska Fishing Lodge-Soldotna B&B